"Legend is overdue for replacement, and an adequate replacement must attend to the process of science as carefully as Hull has done. I share his vision of a serious account of the social and intellectual dynamics of science that will avoid both the rosy blur of Legend and the facile charms of relativism.... Because of [Hull's] deep concern with the ways in which research is actually done, Science as a Process begins an important project in the study of science. It (...) is one of a distinguished series of books, which Hull himself edits."—Philip Kitcher, Nature "In Science as a Process, [David Hull] argues that the tension between cooperation and competition is exactly what makes science so successful.... Hull takes an unusual approach to his subject. He applies the rules of evolution in nature to the evolution of science, arguing that the same kinds of forces responsible for shaping the rise and demise of species also act on the development of scientific ideas."—Natalie Angier, New York Times Book Review "By far the most professional and thorough case in favour of an evolutionary philosophy of science ever to have been made. It contains excellent short histories of evolutionary biology and of systematics (the science of classifying living things); an important and original account of modern systematic controversy; a counter-attack against the philosophical critics of evolutionary philosophy; social-psychological evidence, collected by Hull himself, to show that science does have the character demanded by his philosophy; and a philosophical analysis of evolution which is general enough to apply to both biological and historical change."—Mark Ridley, Times Literary Supplement "Hull is primarily interested in how social interactions within the scientific community can help or hinder the process by which new theories and techniques get accepted.... The claim that science is a process for selecting out the best new ideas is not a new one, but Hull tells us exactly how scientists go about it, and he is prepared to accept that at least to some extent, the social activities of the scientists promoting a new idea can affect its chances of being accepted."—Peter J. Bowler, Archives of Natural History "I have been doing philosophy of science now for twenty-five years, and whilst I would never have claimed that I knew everything, I felt that I had a really good handle on the nature of science, Again and again, Hull was able to show me just how incomplete my understanding was.... Moreover, [Science as a Process] is one of the most compulsively readable books that I have ever encountered."—Michael Ruse, Biology and Philosophy. (shrink)

Drawing on work of the past decade, this volume brings together articles from the philosophy, history, and sociology of science, and many other branches of the biological sciences. The volume delves into the latest theoretical controversies as well as burning questions of contemporary social importance. The issues considered include the nature of evolutionary theory, biology and ethics, the challenge from religion, and the social implications of biology today (in particular the Human Genome Project).

Compares classic and contemporary theories of genetics and evolution and explores the role of teleological thought in biology.

Biological species have been treated traditionally as spatiotemporally unrestricted classes. If they are to perform the function which they do in the evolutionary process, they must be spatiotemporally localized individuals, historical entities. Reinterpreting biological species as historical entities solves several important anomalies in biology, in philosophy of biology, and within philosophy itself. It also has important implications for any attempt to present an "evolutionary" analysis of science and for sciences such as anthropology which are devoted to the study of single (...) species. (shrink)

Intentionality, as Brentano originally introduced the term in modern philosophy, was meant to provide a distinctive characteristic definitively separating the mental from the physical. Mental states have an intrinsic relationship to an object, to that which they are ‘about.’ Physical entities just are what they are, they cannot, by their very essence, refer to anything, they have no ‘outreach,’ as one might put it. Mental states have, as it were, an incomplete essence, they cannot exist at all unless they are (...) completed by something other than themselves, their object. Brentano's position is opposed to all theories which represent the mental as only extrinsically related to the world, that is, to all theories in which mental states are themselves self-sufficient for their own existence and only secondarily relate to the world by means of something external to their nature, e.g., neurological causation, divine intervention, or preestablished harmony. (shrink)

Much has been written about prisoner research and the controversies surrounding prisoners as human subjects. The Institute of Medicine recently released a report addressing some of these issues. This report, which generated further controversy, needs to be fully discussed in the literature and certain aspects are examined in this work. Further, in the body of literature there has been little acknowledgement of the concept of the right of prisoners to be involved in research. This needs to be pursued from an (...) ethical perspective and eventually a legal one. This paper explores that concept and documents some facilities in which a prisoner's right to research has occurred. (shrink)

Intentionality, as Brentano originally introduced the term in modern philosophy, was meant to provide a distinctive characteristic definitively separating the mental from the physical.(1) Mental states have an intrinsic relationship to an object, to that which they are "about." Physical entities just are what they are, they cannot, by their very essence, refer to anything, they have no "outreach", as one might put it. Mental states have, as it were, an incomplete essence, they cannot exist at all unless they are (...) completed by something other than themselves, their object. Brentano's position is opposed to all theories which represent the mental as only extrinsically related to the world, that is, to all theories in which mental states are themselves self-sufficient for their own existence and only secondarily relate to the world by means of something external to their nature, e.g., neurological causation, divine intervention, or pre-established harmony. In these later cases, any mental act whatsoever could be related to any object, or indeed to none, for the relation is external to the nature of the act, it is superimposed on it by outside forces. Brentano's point is that a mental act has, by its very essence, an Intentional object without which it would not be a mental act. It would therefore appear that since causality is an external relationship which could in principle relate any two things regardless of their nature, the Intentional relation between an act and its object cannot be a causal relation. (shrink)

Tomasello offers an evolutionary, palaeoanthropological account of the human origin of objects and objectivity. Husserl gives a phenomenological account of the constitution of objects by intersubjectivity. Comparing the two, I claim that Tomasello’s “naturalized” approach closely parallels Husserl’s transcendental approach.

Four philosophers, Husserl, Wittgenstein, Dennett, and Hegel, who hold for the most part radically different philosophies, all agree on rejecting the notion of atomic entities, of “things-in-themselves,” and insist that objects only make sense – can only be what they are -- in a context.

Language defines human existence. Yet defining language is a fraught project. I use the term "language" to refer to a specific mode of information transfer. First, it is a communicative mode. By communication I mean the information transfer serves a function, that is, an activity that occurs because it has increased the evolutionary fitness of ancestors. Secondly, while all communication is governed by norms, human communication, as opposed to biological communication, is governed by norms that have evolved within the learned (...) traditions of individual cultures. The meaning of an assertion in a culture’s language is the set of commitments to which that culture holds its speakers when they utter that assertion. Syntax has appeared in recent evolution to facilitate and enrich the communicative function, but it is a secondary aspect of language. The defining characteristic of human communication, of "language," -- is its capacity to constitute meaning. (shrink)

Against the concept that objects are defined by their self-contained essence – “thing-in-themselves” – Husserl and Foucault claim they are defined by intersubjectivity or social institutions. I argue that biological and even physical (complex) systems can constitute the unity and meaning of objects.

Individuals with autistic spectrum disorder (ASD) display diverse deficits in social, cognitive and behavioral functioning. To date, there has been mixed findings on the profile of executive function deficits for high-functioning adults (IQ >70) with ASD. A conceptual distinction is commonly made between “cold” and “hot” executive functions. Cold executive functions refer to mechanistic higher-order cognitive operations (e.g., working memory), whereas hot executive functions entail cognitive abilities supported by emotional awareness and social perception (e.g., social cognition). This study aimed to (...) determine the independence of deficits in hot and cold executive functions for high-functioning adults with ASD. Forty-two adults with ASD (64% male, aged 18-66 years) and 40 age and gender matched controls were administered The Awareness of Social Inference Test (TASIT; emotion recognition and social inference), Letter Number Sequencing (working memory) and Hayling Sentence Completion Test (response initiation and suppression). Between-group analyses identified that the ASD group performed significantly worse than matched controls on all measures of cold and hot executive functions (d =.54-1.5). Hierarchical multiple regression analyses revealed that the ASD sample performed more poorly on emotion recognition and social inference tasks than matched controls after controlling for cold executive functions and employment status. The findings also indicated that the ability to recognise emotions and make social inferences was supported by working memory and response initiation and suppression processes. Overall, this study supports the distinction between hot and cold executive function impairments for adults with ASD. Moreover, it advances understanding of higher-order impairments underlying social interaction difficulties for this population which, in turn, may assist with diagnosis and inform intervention programs. (shrink)

Why should anyone be bound by cognitive norms, such as the norms of reason or mathematics? To become a mathematician is to learn to obey the norms of the mathematical community. A self becomes intentional by binding itself to communal norms. Only then can it have the freedom to think or make assertions about the community’s objects -- triangles or imaginary numbers, for example. Norms do not bind selves from the outside: being bound by norms is what constitutes a self.

The self is not a metaphysical object but a mode of temporal organization unified by responsibility. Learning to be responsible constitutes the self as a self-identical entity over time. Responsibility depends on the current self interpreting previous events, attributing them to itself and thereby committing itself for the future. (2004) .

Biological organisms, languages and selves are normative entities, so must be understood in terms of norms. Mechanistic understanding is based on causal necessity, but normative understanding relies on a grasp of the contingencies of evolution, history and personal experience.

Thought is not based on an image that is isomorphic to the object. Descartes, Husserl, Frege, Wittgenstein and Brandom progressively overcome this Aristotelian misconception of the intentionality of thinking.

Examines the issues of self (including gender), truth, and transcendence in classical Chinese and Western philosophy.

The temporal unity of the self cannot be accounted for by the continuity of causal, factual, or contiguous relations between independently definable mental events, as proposed by Locke and Parfit. The identity of the self over time is normative: it depends on the institutional context of social rules external to the self that determine the relationship between past commitments and current responsibilities. (2005).

Kosgaard claims that selves/agents self-constitute during actions by relying on principles such as Kant’s Categorical Imperative. This intellectualist approach neglects the body. Merleau-Ponty considers the “lived body” and its perceptual world as the source of the unity of action, an approach that I extrapolate to all biological organisms.

Explanation is a human activity. Teleological, causal, and evolutionary explanations are all valid forms of responding to particular puzzlements. Reductionism incorrectly assumes there is one absolute explanation. While causal explanation appeals primarily to necessity, evolutionary explanation is based largely on contingency.

Modern selfhood presents itself as autonomous, overcoming emotion by following cognitive, moral and linguistic norms on the basis of clear, rational principles. It is difficult to imagine how such normative creatures could have evolved from their purely biological, non-normative, primate ancestors. I offer a just-so story to make it easier to imagine this transition. Early hominins learned to cooperate by developing group identities based on tribal norms. Group identity constituted proto-selves as normative creatures. Such group identity was not based on (...) autonomous selfhood – such an explanation would be anachronistic -- but on emotional patterning. By imitation, music, dance, ritual and other emotional practices, proto-selves learned how to bind themselves to the norms of their culture. Such conformity was a transitional evolutionary stage between primates and selves. Emotion and rationality are not incompatible: even contemporary selfhood remains rooted in emotional identity. (shrink)

Extreme variation in the meaning of the term “species” throughout the history of biology has often frustrated attempts of historians, philosophers and biologists to communicate with one another about the transition in biological thinking from the static species concept to the modern notion of evolving species. The most important change which has underlain all the other fluctuations in the meaning of the word “species” is the change from it denoting such metaphysical entities as essences, Forms or Natures to denoting classes (...) of individual organisms. Several authors have taken notice of the role of metaphysics in the work of particular biologists. An attempt will be made in this paper to present a systematic investigation of the role which metaphysics has played in the work of representative biologists throughout the history of biology, especially as it relates to their species concepts. (shrink)

Jacobs, in Choosing Character, seems to assume that there are selves already capable of voluntary choice who then choose their character by developing habits. I argue that selves, choice, responsibility and character form a conceptual and practical hermeneutic circle, a whole without which selfhood makes no sense. There can be no selfhood prior to responsible character.

My aim is to give an overview of what minds are and how they came to be. Minds are a product of billions of years of evolution so it is a daunting task to summarize this history in 45 minutes. My attempt will involve vast oversimplifications, highly speculative and condensed “just so” stories, and a great amount of hand waving. In particular, I will presuppose the theory of evolution and will not attempt to either explain it or justify it.

What makes us persons? Is it our bodies, our minds, or our consciousness? For centuries, philosophers have sought to answer these questions. While some believe humans are physical or biological, others claim we have an immaterial soul. This book proposes a new alternative. Selves were formed in evolution through connections and commitments to others when early hominins lived in tribal groups and developed languages. As humans learned to fulfill these commitments, they not only cultivated relationships but also created their personal (...) identities. Their habits of responsibility established their characters and therefore their reputations within their communities. This naturalistic approach proposes that a self is defined by the history of its commitments to cultural and personal norms. While brain processes are required, the self is not some internal, private mind but primarily a role within its community. As technology advances, selfhood could in the future be enabled by electronic, quantum, or other non-biological means. So if a self is formed through norms, could artificial intelligence evolve to have self-identity? (shrink)

Methodological and philosophical foundations in the anthropology of Ruth Benedict and Margaret Mead.

Intuition. Originally an alleged direct relation, analogous to visual seeing, between the mind and something abstract and so not accessible to the senses. What are intuited (which can be derivatively called 'intuitions') may be abstract objects, like numbers or properties, or certain truths regarded as not accessible to investigation through the senses or calculation; the mere short circuiting of such processes in 'bank managers intuition' would not count as intuition for philosophy. Kant talks of our intuiting space and time, in (...) a way which is direct and entirely free from any mediation by the intellect - but this must be distinguished from an alleged pure reception of 'raw data' from the senses; the intuiting is presupposed by, and so cannot depend upon, sensory experience. (shrink)

Outline by Section: INTRODUCTION HUSSERL'S TRANSCENDENTAL POSITION Brentano's Notion of Intentionality Frege's Notion of Sinn Husserl's Transcendental Position Intentional Relations are not Causal. Realism is Wrong, Objects must be Meaningful Psychological States are Empirical. Meanings cannot be In-Themselves, but always for an Ego SEARLE'S THEORY OF INTENTIONALITY CONFRONTATION OF SEARLE'S THEORY WITH THE FOUR THESES Searle Intentionalizes or Trivializes Causation Searle is still a Realist Visual Experience is a Thing-In-Itself Intentional States Presented as Stopping Points CONCLUSION.

My thesis is that modern neurological discoveries overthrow the classical dualism which assigns all the constitutive activity of perception to the mind and leaves the body a purely passive role. The paper is in four parts: first I will present the traditional theory, using Berkeley's concept of activity as the key; then I will summarize the relevant aspects of contemporary neurology; third, the incompatibility of these two approaches will be discussed; finally, I will propose that we must reject the materialistic (...) notion of the body and grant it a power of activity which was formerly held to be the monopoly of the mind. Throughout, I will take the spatialization of sensation as the prime example of a constitutive activity. (shrink)

A self is a temporal unity in which responsibility for past commitments modifies how the present world is experienced and evaluated. This structure is analogous (a) to biological evolutionary changes in perception and (b) to how changes in a computer program determine how it will respond in the future. Responsibility is not an add-on to a self, but the mode of its integration over time. (Presented at Royal Institute of Philosophy Annual Conference, Narrative and Understanding Persons, University of Hertfordshire, UK, (...) 2005). (shrink)

The advent of formal definitions of the simplicity of a theory has important implications for model selection. But what is the best way to define simplicity? Forster and Sober ([1994]) advocate the use of Akaike's Information Criterion (AIC), a non-Bayesian formalisation of the notion of simplicity. This forms an important part of their wider attack on Bayesianism in the philosophy of science. We defend a Bayesian alternative: the simplicity of a theory is to be characterised in terms of Wallace's Minimum (...) Message Length (MML). We show that AIC is inadequate for many statistical problems where MML performs well. Whereas MML is always defined, AIC can be undefined. Whereas MML is not known ever to be statistically inconsistent, AIC can be. Even when defined and consistent, AIC performs worse than MML on small sample sizes. MML is statistically invariant under 1-to-1 re-parametrisation, thus avoiding a common criticism of Bayesian approaches. We also show that MML provides answers to many of Forster's objections to Bayesianism. Hence an important part of the attack on Bayesianism fails. (shrink)

We highlight the various domains of the flavivirus virulence factor NS1 and speculate on potential implications of the NS1 3D structure in understanding its role in flavivirus pathogenesis. Flavivirus non‐structural protein 1 (NS1) is a virulence factor with dual functions in genome replication and immune evasion. Crystal structures of NS1, combined with reconstructions from electron microscopy (EM), provide insight into the architecture of dimeric NS1 on cell membranes and the assembly of a secreted hexameric NS1‐lipid complex found in patient sera. (...) Three structural domains of NS1 likely have distinct roles in membrane association, replication complex assembly, and immune system avoidance. A conserved hydrophobic inner face is sequestered either on the membrane or in the interior of the secreted hexamer and contains regions implicated in viral replication. The exposed variable outer face is presented to cellular and secreted components of the immune system in infected patients and contains candidate regions for immune system modulation. We anticipate that knowledge of the distinct NS1 domains and assembly will lead to advances in elucidating virus‐host interactions mediated through NS1 and in dissecting the role of NS1 in viral genome replication. (shrink)